Clinical Evidence
Clinical Evidence
Precision urine collection that reduces contamination and delivers reliable results.
Peezy Midstream delivers guideline-compliant, precision urine collection that reduces specimen contamination and false positives in women’s UTI and prenatal screening, bringing proven clinical and service benefits to healthcare providers, alongside cost savings and a cleaner, kinder patient experience.
As with any new diagnostic system, we recommend a brief face-to-face introduction for first-time users, after which the process becomes intuitive.
See our excellent Primary Care GP Surgery trial outcome here.
See our IFU animation here.
Published Clinical Evidence
Our clinical evidence confirms efficacy, efficiency and patient satisfaction. Full details below, with links to each paper.
PEEZY MIDSTREAM – Clinical Evidence Summary
| Contamination / Mixed Growth Rate | ||||||
|---|---|---|---|---|---|---|
| Region | Year | Setting / Institution | Patients | Start-Stop-Start Method | Peezy Midstream | Published |
| UK | 2013 | Pennine Acute Hospitals NHS Trust, Urology | 104 | 23% | 5% | Download PDF |
| UK | 2016 | Barts Health NHS Trust, Urology | 66 | 23% | 1.5% | View Image |
| UK | 2017 | Royal Surrey County Hospital | 26 | 9% | 2.5% | Download PDF |
| UK | 2019 | North Devon NHS Orthopaedic and Urology pre-op urines | 100 | 25% | 1% | View Resource |
| UK | 2019 | Public Health Wales Cardiff & Vale Primary Care Board | 119 | 14% | 0% | Download PDF |
| Positive Dips Sent to Lab | ||||||
| Region | Year | Setting / Institution | Patients | Start-Stop-Start Method | Peezy Midstream | Published |
| UK | 2018 | West Herts NHS Trust, Watford Antenatal Clinic (Traditional arm) | 347 | 205 (59%) | – | View Resource |
| UK | 2018 | West Herts NHS Trust, Watford Antenatal Clinic (Peezy arm) | 655 | – | 186 (28.4%) | View Resource |
| USA | 2019 | Loyola Chicago Stritch School of Medicine, Dept. Microbiology & Immunology | 62 | – | Bacterial profiles of Peezy-collected urines differed significantly by multiple diversity indices and had significantly reduced colony-forming units compared to periurethral swabs. | View Resource |
| USA | 2024 | University of California San Diego, OBGYN / Brubaker | 156 | – | Home collection of urogenital microbiome samples for research is feasible, with comparable success to clinical research centre collection. | View Resource |
Research on Peezy Midstream may reveal a 2021 study from Oxford Nuffield published in the British Journal of General Practice. Like first time use of any device or clinical item, first-time instruction is recommended.
The study paper confirms that while detailed guidance on the traditional start-stop-start method was given to each patient in the traditional arm – and that this can be unusual on the frontline of primary care – patients in the Peezy Midstream arm were simply given a pack and asked to use it, with no guidance and no assurance that the patient had a full bladder (as recommended on the pack). The author claims that a full bladder was not viable for patients presenting with UTI, a factor that has not arisen in real-world studies either in Primary Care or Antenatal Clinics, all of which have yielded excellent clinical and diagnostic outcomes with good patient experience.
You can read the paper here together with Dr Vincent Forte’s response.
As a result of this trial, we have improved our Instructions for Use, making the need for a full bladder more pronounced.
We await NICE agreement to re-publish our real world evidence, which was removed from its platform in 2024 in favour of this one academic study.